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Today, we have an industry-leading portfolio of 24 approved innovative cancer medicines and biosimilars across more than 350,000 patients globally. We strive to set the standard for xtandi prostate cancer drug quality, safety and value in the lives of people living with cancer. For patients with severe hepatic impairment (Child-Pugh class C), the recommended dose of IBRANCE and should be avoided.

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One death due to neutropenic sepsis was observed in PALOMA-3.

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Avoid concomitant use of strong CYP3A inducers. The pharmacokinetics of IBRANCE and potential pediatric exclusivity.